Nov 22, 1859. Charles Darwin’s monumental work, On the Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life, was published on this date by London publisher John Murray. The print run of 1,250 (priced at 15 shillings) sold out the same day. A second print run of 3,000 in December also sold quickly.The book immediately generated a firestorm of public and private discussion. The word evolution did not appear until the 1872 (last) edition of Origin.